Yoga

Manobala V R et al. (2026) · Bioinformation

This single-arm pilot trial with 30 participants explored whether a 90-day Siddhar yogam programme could reduce the symptom burden of varicose veins, which are dilated, twisted veins of 3 mm or more in the legs. Siddhar yogam belongs to the Siddha system of medicine, a South Indian tradition that explains illness through three humors, Vatham (air), Pitham (fire) and Kabham (water), and counts Siddhar yogam among its Kayakarpam (rejuvenation science) methods. The practice combines yoga postures, controlled breathing and meditation. The authors note that no standardized, non-invasive therapy exists for varicose veins, a condition they say affects about 5% of people in India. The 30 patients (10 men and 20 women, aged 30 to 55) were recruited at the National Institute of Siddha's Ayothidoss Pandithar Hospital. All practised the same 35-minute routine for 90 days: a few minutes of relaxation, 21 minutes of postures such as raised-leg pose, half plough, inverted pose and cycling pose, and 5 minutes of Thirumoolar breathing practice. Symptoms and quality of life were scored with the Aberdeen Varicose Vein Questionnaire (AVVQ), where a lower score means less impact, before and after the programme. There was no comparison group. Average AVVQ scores dropped from 16.2 to 12.0 (a fall of 4.2 points; reported as significant at p < 0.05 by Wilcoxon signed rank test). Most participants (over 85%) reported long periods of standing, and the Siddha assessments, which grade humors, body constituents and an eight-fold examination, showed derangement mainly in Vatham and Pitham before treatment and a reduction in these findings afterwards, though the paper gives no figures for that change. The authors suggest the postures lower pressure in the leg veins and help blood return to the heart by working the calf muscles, but they did not measure this. Because the trial had one arm, no follow-up and only one outcome measure, and excluded severe cases, the authors say the efficacy of the regimen cannot be established. They recommend larger randomized trials.

Zheping Quan et al. (2026) · Frontiers in immunology

This systematic review and network meta-analysis of 16 randomized controlled trials (943 participants) explored which forms of exercise are linked to better outcomes in irritable bowel syndrome (IBS). IBS is a functional gut disorder, meaning the bowel looks normal on testing but causes recurring abdominal pain and altered bowel habits, and it often occurs alongside anxiety and depression. The authors framed the gut and brain as communicating through the brain-gut axis, with the immune system, intestinal barrier and gut microbiota also involved. A network meta-analysis is a statistical method that compares several treatments at once, even when some were never tested head to head, and ranks them using SUCRA, a percentage score where higher values mean a greater chance of being best. The included trials, published between 2004 and 2025, tested yoga, Pilates, Baduanjin (a traditional Chinese gentle movement routine), running and moderate-intensity aerobic exercise for 4 to 24 weeks. Participants were adults with constipation-predominant, diarrhea-predominant or mixed IBS, mostly in Asia, Europe and North America. Comparison groups received conventional treatment, dietary advice, probiotics or education. Researchers measured symptom severity with the IBS Symptom Severity Scale, quality of life with the IBS Quality of Life scale, and mood with anxiety and depression scores. Exercise improved several outcomes. Depression scores fell overall (SMD -0.56, a moderate-sized benefit), though heterogeneity was very high (I2 = 95%, meaning results varied widely between trials), and yoga alone was not significant. Anxiety dropped with yoga (SMD -1.82), Pilates (SMD -3.84) and aerobic exercise (SMD -6.31). Symptom severity improved with running (MD -72.68 points), Pilates (-71.32), aerobic exercise (-46.50) and Baduanjin (-16.94), with running ranked first (SUCRA 90.3%). Quality of life ranked Baduanjin first (99.9%) and yoga second (80.1%), while aerobic exercise showed no significant difference from conventional treatment. In subscale analyses, Pilates cut pain severity (MD -17.90) and aerobic exercise improved dysphoria, activity interference, body image, health worries and relationships, while yoga helped only bowel satisfaction and interference with life. Rankings differed by outcome, which the authors describe as functional specificity. The authors describe exercise as a safe, low-cost non-pharmacological option that may hold value in comprehensive IBS management, but the evidence carries clear limits. Heterogeneity was high, many trials did not clearly blind participants or assessors, and some effect sizes were unusually large, which the authors attribute to small samples. Study counts were reported inconsistently across sections, and safety was not analysed. Too few trials came from outside East Asia to judge differences across ethnic groups. The immune mechanisms remain unproven, and the authors call for trials that add immune markers, biomarkers and gut microbiome measures.

Lei Yi et al. (2022) · Journal of translational medicine

This randomized controlled trial with 94 women explored whether a 12-week yoga program could ease symptoms of post-traumatic stress disorder (PTSD, a condition marked by intrusive memories, avoidance of reminders, and heightened arousal following a traumatic event) after a motor vehicle accident. All participants had PTSD tied specifically to a car, motorcycle, or pedestrian accident that occurred at least three months earlier. The intervention used Kripalu yoga, a style emphasizing gentle self-observation and the connection between mind and body rather than intensive physical exertion, compared against an active control condition built around social conversation and board games. Ninety-four women were randomly assigned to a yoga group (47) or control group (47); 37 and 39, respectively, completed the trial through a 3-month follow-up. The yoga group attended six 45-minute sessions across 12 weeks, practicing breath awareness, body-focused attention during postures, and tolerance of physical discomfort under a yoga instructor's guidance. The control group met on the same schedule for daily-life conversation and games. Psychological distress was measured with two self-report instruments, the Depression Anxiety Stress Scales (DASS-21) and the Impact of Event Scale-Revised (IES-R), completed at baseline, immediately after the program, and three months later. After the program, the yoga group's total IES-R score, covering intrusion, avoidance, and hyperarousal symptoms, was significantly lower than the control group's (p = 0.01, meaning the difference was unlikely due to chance), with the difference concentrated in intrusion (p = 0.002) and avoidance (p < 0.001) rather than hyperarousal, which did not differ significantly. Intrusion and avoidance remained significantly lower in the yoga group three months later (p = 0.037 and p = 0.005). On the DASS-21, total distress scores were significantly lower in the yoga group both immediately after the program (p = 0.043) and at three-month follow-up (p = 0.024), with depression (p = 0.033, then p = 0.004) and anxiety (p < 0.001, then p = 0.035) each significantly reduced compared with control. The stress subscale of the DASS-21 showed no significant difference between groups at either timepoint. Both groups improved somewhat over time, including the control group, which the authors attribute partly to the social contact built into the comparison condition. The authors describe the results as preliminary evidence that a structured yoga program reduced depression, anxiety, and the intrusion and avoidance symptoms of PTSD in women following a motor vehicle accident, while finding no measurable effect on stress or hyperarousal. The trial enrolled a relatively small, single-site sample of Chinese women, tested only one yoga style, and relied entirely on self-report questionnaires rather than clinician-rated diagnostic measures. The authors point to comparing yoga styles and isolating which specific session components drive symptom change as directions for future research.

Hong Xu et al. (2024) · Menopause (New York, N.Y.)

This meta-analysis pooled 11 randomized trials testing whether mind-body exercise programs, including tai chi, yoga, Pilates, qigong, and mindfulness-based stress reduction (MBSR, an 8-week meditation and gentle-movement program), help women going through perimenopause or postmenopause, a life stage marked by declining estrogen that can weaken bones, disrupt sleep, and affect mood. These practices pair physical movement with controlled breathing and present-moment attention, offering a non-drug alternative for women wary of hormone therapy's cancer-risk profile. The review combined 11 trials from six countries, involving just over 1,000 women, comparing mind-body exercise groups against women who continued their normal daily activities without a structured exercise program. The trials varied widely, from 6-week programs to a full year, and used five different practices, so results were combined statistically using methods that account for this variety. Across the pooled data, mind-body exercise meaningfully helped on every measure studied: bone density improved (drawing on Pilates and tai chi trials), sleep quality improved (drawing on Pilates, yoga, qigong, and MBSR trials), and both anxiety and depression symptoms dropped substantially (also drawing on that same four-practice group), while fatigue eased too. The anxiety and depression improvements were the largest effects seen, though the studies contributing to them varied considerably in their findings (a statistical marker called heterogeneity was high), meaning some trials showed much bigger benefits than others. Taken together, the findings support mind-body exercise as a safe, reasonable option for managing the physical and emotional challenges of the menopause transition, giving women another evidence-based choice beyond hormone therapy. Because the analysis pooled several different practices together rather than testing each one separately with its own effect size, it shows that mind-body exercise as a category helps, without pinpointing exactly how much benefit comes from any one specific practice like yoga versus tai chi. The individual trials were also generally small and only partially blinded, since exercise programs are hard to disguise from participants.

Galib Ruknuddin et al. (2026) · JMIR research protocols

This paper is not a study of a treatment — it is a detailed, PROSPERO-registered plan (protocol) for a future systematic review that will evaluate India's AYUSH traditional medicine systems (Ayurveda, yoga and naturopathy, Unani, Siddha, Sowa Rigpa/Tibetan medicine, and homeopathy — governing prevention and personalized care) for managing prediabetes and type 2 diabetes. Diabetes affects roughly 537 million people worldwide, a number expected to more than double by 2050, and India alone had over 74 million cases in 2021 — with about half going undiagnosed — making a clear-eyed evidence review of its traditional treatment options a genuine public-health priority. Once underway, two independent researchers will search major databases (PubMed, Scopus, Web of Science, Embase) plus AYUSH-specific sources, screening for studies conducted in India that test any of these six systems — whether used alone or alongside standard diabetes care — measuring outcomes like blood sugar levels (fasting and after meals), long-term blood sugar control (HbA1c), and insulin resistance, alongside safety data. As of this publication, there are no results to report (the review had not yet started; database searching was planned for September 2025). What the protocol does establish is exactly how quality will be judged: each study will be scored with standard tools (from the NIH, and the Cochrane risk-of-bias tool for randomized trials) and then sorted into a visual "evidence map" — graded green, yellow, or red by the World Health Organization's A/B/C evidence-quality scale — showing at a glance where each traditional system has strong support and where the gaps are. The completed review and its findings are expected around December 2026, with publication in early 2027. For now, the practical takeaway is that this protocol tells us what will be studied and how carefully, not what was found. Until the finished evidence map is published, none of the six systems named here has established evidence for diabetes management; the protocol itself states upfront limitations even for the eventual review: English-language sources only, India-based studies only, and no pooled statistical meta-analysis planned.

Shamini Jain et al. (2015) · Global advances in health and medicine

This study explores the concepts of consciousness and subtle energy within Indo-Tibetan philosophical and medical systems, aiming to enhance cross-cultural dialogue on the biofield. By examining the similarities and differences among Vedic, Jain, and Tibetan traditions, the research seeks to inform contemporary biofield science and improve understanding of health and healing practices. The integration of traditional knowledge with modern scientific methods is emphasized as a means to bridge the gap between ancient wisdom and contemporary health sciences. The study employs a descriptive analysis to investigate the relationship between ancient Indo-Tibetan systems and modern biofield science. It does not involve a specific intervention or treatment but rather focuses on the philosophical concepts related to consciousness and subtle energy. The research highlights the importance of introspective inquiry in these ancient systems, paralleling modern scientific findings in health and wellness. The objective is to foster deeper cross-cultural dialogue and enhance understanding of biofields through the exploration of these traditional concepts. The findings indicate that there are significant similarities and differences in the understanding of biofields across the three traditions studied. The authors suggest that integrating traditional diagnostic methods with contemporary biomarkers could inform treatment options and improve health outcomes. However, limitations include the need for more empirical studies to validate the proposed connections and the challenges of integrating diverse methodologies. The study aligns with previous research that has explored genetic and metabolic differences associated with traditional medicine systems, suggesting a valuable intersection between traditional and modern approaches. The implications of this research are significant for practitioners and researchers in health and healing. By incorporating holistic approaches and traditional diagnostic methods alongside modern biomarkers, practitioners may enhance health assessments and treatment options. Key limitations include the necessity for empirical validation of the proposed links and the challenges in integrating methodologies from Eastern and Western perspectives. Future research should focus on empirical investigations of biofield practices and their effects on health outcomes, particularly regarding the mechanisms of subtle energy interactions.